Buprenorphine (Suboxone or Sublocade)
We use several medications to aid in treatment. For opioid use disorder, buprenorphine (Suboxone or Sublocade) is the most commonly recommended treatment due to good effectiveness and tolerability. Buprenorphine is a partial opioid agonist, providing good stimulation of the opioid receptors to alleviate cravings and withdrawals, while simultaneously blocking other opioids due to to its strong binding to the receptors.
Suboxone is the brand name for sublingual buprenorphine. These are tablets or film strips placed under the tongue daily for opioid use disorder treatment. Other brands include Zubsolv and Bunavail.
Sublocade is a once monthly injection of buprenorphine. After switching to this treatment, patients are often more consistent with their treatment and notice fewer effects from blood level changes in buprenorphine level between doses.